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| 基于光流控技术的蛋白光学检测分析技术 |
| Optical detection of protein analysis based on optofluidics technologies |
| 投稿时间:2025-03-10 |
| DOI:10.3969/j.issn.1005-5630.202503100046 |
| 中文关键词: 蛋白分析 标记物 生物标志物检测 光流控技术 |
| 英文关键词:protein analysis markers biomarker detection optofluidics |
| 基金项目: |
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| 中文摘要: |
| 蛋白的异常表达或功能紊乱与多种疾病密切相关,因此,蛋白分析在生物研究、疾病诊断方面具有不可替代的作用。传统的蛋白分析技术存在着自身局限性,如灵敏度不够、操作复杂、无法实时监测,难以满足临床诊断和精准医疗的需求。近年来,光流控技术的出现为蛋白分析提供了新的解决方案,不仅能够实现高灵敏度检测,还能对分子间的相互作用进行实时监测,获取动态信息。此外,光流控技术还具有检测多个目标蛋白的能力,显著提高了分析效率。 |
| 英文摘要: |
| Abnormal expression or dysfunction of proteins is closely related to a variety of diseases, therefore, protein analysis has an important role in biological research and disease diagnosis. Traditional protein analysis technology still has its own limitations, such as insufficient sensitivity, complex operations, and no real-time monitoring, which makes it difficult to meet the needs of clinical diagnosis and precision medicine. In recent years, the appearance of optofluidic technology provides a new solution for protein analysis. Not only can it achieve high sensitivity detection, but also real-time monitoring of interactions between molecules to obtain dynamic information. In addition, optofluidic technology has the ability to detect multiple target proteins, which significantly improves the analysis efficiency. |
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