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| 以金刚石氮−空位色心为探针的亚衍射级成像技术及应用 |
| Sub-diffraction imaging technology and application using diamond nitrogen-vacancy color center as probe |
| 投稿时间：2024-04-07 |
| DOI：10.3969/j.issn.1005-5630.202404070068 |
| 中文关键词: 亚衍射级成像 氮−空位色心 荧光探针 |
| 英文关键词:sub-diffraction imaging techniques nitrogen-vacancy(NV) color centers fluorescent probe |
| 基金项目:国家自然科学基金(52375441) |
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| 摘要点击次数: 948 |
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| 中文摘要: |
| 考虑到传统光学显微镜受光学衍射限制，分辨率无法满足生物、材料、微机电系统等领域的科研需求，因此需要借助基于荧光探针的亚衍射级成像技术。相对于传统荧光探针，金刚石氮?空位色心具有稳定的发光特性、独特的光学亮态、暗态转换特性、较长的电子自旋相关时间以及生物兼容性等优异性能，使其成为新型探针在亚衍射级成像领域发挥关键作用。本文将介绍氮?空位色心作为荧光探针的两种机理，并探讨三类基于荧光探针的亚衍射级显微镜技术，总结氮?空位色心在这些亚衍射级成像技术中的应用，并对其应用成果进行综合分析和比较。最后，展望氮?空位色心在这一领域的未来应用前景。 |
| 英文摘要: |
| Considering that conventional optical microscopes are limited by Abbe diffraction diffraction, the resolution cannot meet research needs in the fields of biology, materials, and microelectromechanical systems, so some sub-diffraction imaging techniques based on fluorescent probes are needed for science research. Compared with traditional fluorescent probes,diamond nitrogen-vacancy(NV) color centers have stable luminescence characteristics, unique optical bright and dark state conversion characteristics, long electron spin correlation time, biocompatibility and other excellent characteristics, which can become a new type of probe to play an important role in the field of subdiffraction imaging. This paper introduced two mechanisms of NV color centers as fluorescent probes, three types of fluorescent probe-based subdiffraction microscopy techniques, summarized and compared the applications of NV color centers in these subdiffraction imaging techniques, and finally prospected their applications. |
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