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| 纳米CT造影剂在肺部疾病诊疗中的研究进展 |
| Research progress of nanoparticle CT contrast agents in the diagnosis and treatment of pulmonary diseases |
| 投稿时间：2024-04-02 |
| DOI：10.3969/j.issn.1005-5630.202404020065 |
| 中文关键词: 纳米CT造影剂 肺部疾病 诊疗 |
| 英文关键词:nano CT contrast agent lung disease diagnosis and treatment |
| 基金项目:国家重点研发计划(2021YFE0111300) |
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| 摘要点击次数: 832 |
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| 中文摘要: |
| 随着慢性阻塞性肺疾病和肺癌等肺部疾病日益威胁全球健康，开发有效的诊断和治疗方法变得至关重要。基于纳米颗粒的计算机断层扫描(computed tomography，CT)造影剂，特别是基于金的纳米颗粒，由于其卓越的X射线吸收能力和生物相容性而成为研究的焦点。本文简要介绍了计算机断层扫描技术，详细阐述了基于纳米颗粒的CT造影剂在肺部疾病诊断和治疗中的应用进展，重点介绍了基于金的纳米颗粒及其改性产品的发展。讨论了当前技术面临的挑战和未来发展方向。该研究强调，基于纳米颗粒的CT造影剂在肺部疾病的精确诊断和治疗方面潜力巨大。 |
| 英文摘要: |
| As chronic obstructive pulmonary disease and lung cancer, among other lung diseases, increasingly threatened global health, the development of effective diagnostic and treatment methods became paramount. Nanoparticle-based computed tomography (CT) contrast agents, especially those based on gold nanoparticles, became the focus of research due to their outstanding X-ray absorption capacity and biocompatibility. This paper briefly introduced CT imaging technology and elaborated on the application progress of nanoparticle-based CT contrast agents in the diagnosis and treatment of lung diseases, with a particular emphasis on gold nanoparticles and their modified derivatives. The current challenges and future directions of the technology were discussed. The study emphasized the enormous potential of nanoparticle-based CT contrast agents in the precise diagnosis and treatment of lung diseases. |
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