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| HPV基因芯片检测装置的匀光照明设计 |
| Uniform illumination design of HPV gene chip detection device |
| 投稿时间：2018-07-13 |
| DOI：10.3969/j.issn.1005-5630.2019.03.012 |
| 中文关键词: HPV基因芯片 矩形LED阵列 匀光照明 灰度均匀度 |
| 英文关键词:HPV gene chip rectangular LED array uniform illumination gray level uniformity |
| 基金项目:福建省科技重大专项项目（2013YZ0002、2014YZ0001） |
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| 中文摘要: |
| 人乳头瘤病毒（HPV）基因芯片检测装置可读取与分析HPV芯片的杂交点信号值，进而区分不同的HPV病毒类型，而检测装置照明的均匀性关系到HPV芯片图像处理算法的可靠性与难度。为实现均匀照明，优化了矩形LED阵列排布并配置匀光扩散板。首先，分析单个LED灯珠的辐射强度分布，建立矩形LED阵列的理论模型；然后，在仿真软件中建立4行8列的矩形LED阵列模型；最后，搭建HPV基因芯片检测装置进行实验测试。实验结果表明，该照明系统能使70 mm×20 mm的目标被照面的灰度均匀度达到95.6%，满足了HPV基因芯片检测装置均匀照明的要求。 |
| 英文摘要: |
| The human papilloma virus (HPV) gene chip detection device can read and analyze the hybrid point signal values of the HPV chip to distinguish different HPV virus types. The uniform illumination of the device is related to the difficulty and reliability of the HPV chip image processing algorithm. To achieve uniform illumination, the rectangular LED array is arranged and the uniform light diffusing plate is arranged. Firstly, the radiation intensity distribution of a single LED lamp bead is analyzed to establish a theoretical model of the rectangular LED array. Then, a rectangular LED array model of 4 rows and 8 columns is established in the simulation software. Finally, the HPV gene chip detection device is set up for experimental testing. The experimental results show that the illumination system has a gray level uniformity of 95.6% in the target surface of 70 mm×20 mm, which meets the uniform illumination requirements of the HPV gene chip detection device. |
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