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| 激光诱导空泡在生物医学中的应用 |
| Application of laser induced cavitation in biomedicine |
| 投稿时间：2018-01-30 |
| DOI：10.3969/j.issn.1005-5630.2018.04.014 |
| 中文关键词: 激光诱导空泡 微流控 生物医学 |
| 英文关键词:laser-induced cavitation microfluidics biomedicine |
| 基金项目: |
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| 中文摘要: |
| 激光诱导空泡现象从20世纪中期被发现之后，就受到了广泛的关注，而近年来研究热点之一的微流控技术，由于在物理尺寸上与激光诱导空泡尺度匹配，近年来研究人员已经将这两个技术融合在一起应用于生物医学领域。通过细胞膜穿孔给细胞微注射药物、通过红细胞的形变量的大小来检测红细胞是否发生病变、通过荧光标记技术来筛选细胞以及降低眼部虹膜切割手术带来的副作用等，综述了激光诱导空泡结合微流控生物芯片在生物医学中的应用，展望了激光诱导空泡现象在生物医学中应用的方向。 |
| 英文摘要: |
| Laser-induced cavitation has received widespread attention since the middle of the last century.In recent years,microfluidics,one of the hot topics in the field of laser-induced cavitation,have been studied in the recent years because of its physical size matching with laser-induced cavitation.Reserachers have combined these two technologies into the biomedical field recently.This review summarizes the applications of laser-induced vacuolization and microfluidic biochips in the biomedical applications.For example,microinjection of drugs into the cells by perforation of the cell membrane by measuring the amount of red blood cell deformation to detect whether the red blood cells lesions,fluorescence screening technology to screen cells and reduce eye iridectomy surgery side effects.Finally,the application of laser-induced vacuolization in biomedicine is discussed. |
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