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| MTT试验筛检49种单体激光光敏剂 |
| Screen Test of 49 Single Photosensitizer Using MTT Assay |
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| DOI: |
| 中文关键词: MTT试验,激光光敏剂,肿瘤细胞 |
| 英文关键词:MTT Assay, Photosensitizer, Cancer Cell |
| 基金项目: |
| 何立明 郑树 郁琳琳 蔡心涵 吴金民 |
| 浙江医科大学肿瘤研究所!杭州,310009,浙江医科大学肿瘤研究所!杭州,310009,浙江医科大学肿瘤研究所!杭州,310009,浙江医科大学肿瘤研究所!杭州,310009,浙江医科大学肿瘤研究所!杭州,310009 |
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| 中文摘要: |
| 用MTT试验方法比较49种单体结构激光光敏剂的光动力学效应,结果显示50%肿瘤细胞抑瘤率位于前10位的单体光敏剂结构以血卟琳类为主,目前临床上试用的光敏剂血卟啉类单甲醚PSD-007处第17位。MTT方法用于筛检多种光敏剂具有简便,快速和数据可靠的优点。 |
| 英文摘要: |
| The comparative test was performed among 49 single photosensitizers. The ranks of the first ten effectives were mainly the kinds of hematoporphyrins,whicn were inhebited more than 50% tumor cells. The photosensizer, PSD-007, which has been already used in clinical test,was ranked at 17th. MTT assay is a speedy and efficent metnodor com paring photosentizers. |
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